SUMMARY

At ASCO 2024, the first results from the phase III NADINA study were presented. Furthermore, the final analysis of the COMBI-AD study demonstrated that one year of adjuvant dabrafenib/trametinib maintains longterm survival benefit in AJCC stage III melanoma. Finally, ASCO featured some interesting presentations on novel strategies to treat melanoma, including the personalised neoantigen vaccine mRNA-4157, the tumour infiltration lymphocyte cell therapy OBX-115, the enhanced oncolytic virus RP2 and neoadjuvant daromun.

(Belg J Med Oncol 2024;18(5):216–20)