BJMO - volume 14, issue 2, march 2020
Y. Raskin MD, G. Vos MD, M. Albersen MD, PhD
This article describes the case of a 77-year old patient in whom a brownish bleeding glans lesion led to the diagnosis of a stage pT4b ulcerating melanoma of nodular subtype on excision biopsy, with a suspect lymph node in the left inguinal region. There was no evidence of nodal or distant metastatic disease. Punch biopsy confirmed nodal disease on the left side. Consequently, a complete glansectomy combined with an iliacofemoral lymphadenectomy was performed on the left side, as well as a sentinel procedure on the right side. Pathology showed residual melanoma in situ in the glans and one necrotic adenopathy (1/8) in the inguinal lymphadenectomy. For this node positive melanoma, the multidisciplinary team meeting agreed to start with nivolumab. Based on the ‘Melanoma Focus’ ano-uro-genital (AUG) mucosal melanoma guidelines, the current recommendations of practice are highlighted. However, the available evidence on AUG mucosal melanoma, and especially penile mucosal melanoma, is very limited.
(BELG J MED ONCOL 2020;14(2):74–9)
Read moreBJMO - volume 13, issue 7, november 2019
A. Coveliers MD, M-P. Graas MD, J. Weerts MD, N. Blétard MD, C. Focan MD, PhD
This oncocase reports the exceptional case of a 65-year-old woman presenting a Demons-Meigs syndrome characterised by dyspnoea issuing from a transsudative pleural effusion together with an important unilateral right ovarian mass and ascites. The diagnosis of a Brenner type histology, a rare and generally benign ovarian affection, was obtained after complete surgical removal of the ovarian tumour. Once discharged, the patient entered in a sustained complete response and thus potential cure.
(BELG J MED ONCOL 2019;13(7):301–4)
Read moreBJMO - volume 13, issue 7, november 2019
C. Soenens MD, G. De Meerleer MD, PhD, M. Albersen MD, PhD, H. Van Poppel MD, PhD, B. Beuselinck MD, PhD
Based on a case report of a 47-year old male with primary bone metastatic renal cell carcinoma, the current treatment options are reviewed in this article.
(BELG J MED ONCOL 2019;13(7):305–8)
Read moreBJMO - volume 13, issue 6, october 2019
C. Debeuckelaere MD, A. Van Goethem MD, G. Maleux MD, PhD, H. Prenen MD, PhD
Percutaneous balloon vertebroplasty (PVP) is an effective treatment for pathological vertebral compression fractures in oncological patients. The procedure is considered safe and the analgesic effect is fast and long lasting. Seeding metastases after PVP are a rare complication. At present, there is no standard of care how to prevent or treat this complication. Further research is necessary to determine preventive measures.
(BELG J MED ONCOL 2019;13(6): 255–257)
Read moreBJMO - volume 13, issue 6, october 2019
B. Dullens MD, C. Bourgain MD, PhD, W. Ceelen MD, PhD, W. Wynendaele MD, PhD
This article describes two cases of malignant peritoneal mesothelioma (MPM), which highlights the diversity of the disease and the diagnostic pitfalls. The risk factors, symptoms, molecular pathogenesis and the daily clinical relevance are discussed.
(BELG J MED ONCOL 2019;13(6): 251–254)
Read moreBJMO - volume 13, issue 4, june 2019
X. Mortiers MD, H. Vandeursen MD, PhD, T. Adams MD, T. Van den Mooter MD
Breast cancer often metastasises to bone, lymph nodes, liver and lung. In this case report, we present a 75-year-old woman with a suspicious mammography and ultrasound of the breast who had a synchronous painless renal lesion. On computed tomography, the renal mass was suspected of being a primary lesion of the renal pelvis, but anatomopathological examination of the nephro-ureterectomy specimen revealed that it was a metastatic deposit of invasive lobular adenocarcinoma of the breast.
(BELG J MED ONCOL 2019;13(4):132–134)
Read moreBJMO - volume 13, issue 3, may 2019
R. De Bock MD, D. Debaere MD, S. Deloose MD, M. Gallant MD, B. Deconinck MD, A. Nollet MD
Tumoral melanosis can be a manifestation of completely regressed melanoma that presents as a possibly suspicious pigmented lesion, with histology showing dense infiltration of benign melanophages. This case report describes a unique case of a 32-year-old carpenter diagnosed with a metastasis located at the gastric fundus, three years after primary diagnosis of a malignant melanoma at the right shoulder. Despite the fact that combined immunotherapy with ipilimumab plus nivolumab could only be administered once due to the development of severe colitis grade 2-3, a control gastroscopy after four months reveals macroscopic alteration of the gastric metastasis with histological regression to benign tumoral melanosis.
(BELG J MED ONCOL 2019;13(3):106–109)
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