Articles

Impact of treatment delays in patients with head and neck cancer

BJMO - volume 18, issue 2, march 2024

D. Schrijvers MD, PhD, S. Mignon MD, M. Brands MD, S. van Roy MD, S. De Schepper MD, N. Van Bruaene MD, D. Nevens MD, PhD, N. Meireson MD

SUMMARY

Head and neck cancer is a complex cancer that involves multiple disciplines (surgery, radiotherapy, systemic therapy). The timely start of surgery and radiotherapy is of utmost importance since the time between the start of treatment is related to overall survival. A delay in surgery increases overall mortality by 6%, while a delay in radiotherapy increases overall mortality by 9%. In this article, the importance of a short time to start treatment in patients with head and neck cancer is discussed.

(BELG J MED ONCOL 2024;18(2):46–8)

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Primary leiomyosarcoma of the thyroid: case report and review of the literature

BJMO - volume 12, issue 2, march 2018

E. Verhelst MD, S. De Schepper MD, S. Declercq , D. Schrijvers MD, PhD

Summary

Primary leiomyosarcoma of the thyroid is a very rare tumour with an unfavourable prognosis. We present a sixty-year-old woman with a localised primary thyroid leiomyosarcoma. Despite a complete resection, a recurrence of the tumour was noticed six months later. After induction chemotherapy with ifosfamide and doxorubicin, the patient had renewed extensive surgery with removal of a tumour remnant and several lymph nodes. This was followed by radiotherapy. Eighteen months after diagnosis the patient is still alive and free of tumour on PET-CT. The case illustrates the high recurrence potential of a primary thyroid leiomyosarcoma despite a complete initial resection, but also the success of aggressive combined treatment.

(BELG J MED ONCOL 2018;12(2):75–78)

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