BJMO - volume 18, issue 7, november 2024
L. Smets MSc, K. Haustermans MD, PhD, A. Wolthuis MD, PhD, G. Bislenghi MD, PhD, E. van Cutsem MD, PhD, L. Debrun BSc, G. de Hertogh MD, PhD, A. D’Hoore MD, PhD, R. Dresen MD, PhD, G. Rasschaert MD, X. Sagaert MD, PhD, S. Tejpar MD, PhD, F. van Herpe MD, J. Dekervel MD, PhD
The multidisciplinary management of rectal cancer is an evolving field, and these guidelines seek to offer direction for treating this condition. A tailored treatment approach should be based on a multi-disciplinary tumour board discussion taking into account tumour staging, patient performance status, and expectations. Patients with node-negative T1 rectal cancer can be managed by a local excision. In patients with early rectal cancer, primary surgery is the standard-of-care. In some of these patients, an organ-sparing approach by long-course chemoradiotherapy can be an alternative. A total neoadjuvant therapy (TNT)-approach consisting of a combination of (chemo)radiotherapy and chemotherapy is preferred for locally advanced disease.
(BELG J MED ONCOL 2024;18(7):271–278)
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