Articles

Nivolumab/ipilimumab-induced cerebral vasculitis in stage IIIc melanoma: A case report

BJMO - volume 17, issue 4, june 2023

E. van Gogh MD, L. Baisier MD, P. Reyntiens MD, J. Liu MD, M. Rasschaert MD, PhD

SUMMARY

Immunotherapy has revolutionised cancer therapy for specific tumour types. The dismal prognosis of melanoma patients with advanced stage has improved but remains poor. With the increasing use of these monoclonal antibodies, toxicities are becoming more prevalent. Neurological adverse events are still rare but have an enormous impact on the continuum of care. This study reports a case of a 70-year-old man with stage IIIc melanoma who presented with cerebral vasculitis after rechallenge therapy with ipilimumab/nivolumab.

(Belg J Med Oncol 2023;17(4):128–31)

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