Articles

Lung cancer screening in 2022: How should we screen optimally?

BJMO - volume 16, issue 6, october 2022

J.P. Van Meerbeeck MD, PhD, A. Snoeckx MD, PhD

SUMMARY

On the brink of the implementation of lung cancer screening, the road from a controlled clinical trial to the real world is long, winding and not without hurdles. The latter will be addressed to come to an optimal lung cancer screening environment in Belgium.

(BELG J MED ONCOL 2022;16(6):279–86)

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Tissue is the issue

BJMO - volume 15, issue 1, january 2021

M. Kukhalashvili MD, JB. Vermorken MD, PhD, T. van den Wyngaert MD, PhD, A. Snoeckx MD, PhD, M. Lammens MD, PhD, M. Peeters MD, PhD, P. Specenier MD, PhD

SUMMARY

Multimodal therapy, including preoperative chemoradiotherapy followed by total mesorectal excision, has become the standard treatment for patients with locoregionally advanced rectal cancer.1 We report on a 54- year old female patient with rectal adenocarcinoma cT3N0M0, who was treated with neoadjuvant chemo-radiotherapy (capecitabine 825 mg/m² BID 5 days/week + 45 Gy in 25 fractions) followed by total mesorectal excision and adjuvant capecitabine for six months. Eleven weeks after the start of adjuvant capecitabine, she presented with dyspnoea, non-productive cough, shortness of breath, chest wall pain, and decrease of physical activity, for which she was admitted to the Antwerp University Hospital (UZA) in Edegem. Computed tomography (CT) revealed pulmonary emboli, enlarged mediastinal and hilar lymph nodes, and multiple micronodules in both lungs. Radiologic findings were suggestive of metastatic lymph nodules and numerous pulmonary metastases. However, pathological diagnosis showed nude granulomas without necrosis without evidence of tumour. Our case illustrates that sarcoid-like lesions may mimic lung metastases in cancer patients being treated with chemotherapy and that tissue still remains the issue.

(BELG J MED ONCOL 2021;15(1):40-3)

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