Journal issues > Issue 7, November 2024 > Appropriateness and optimal sequence of treatments for metastatic castration-resistant prostate cancer: Outcomes of a Belgian and Dutch multidisciplinary consensus meeting

Appropriateness and optimal sequence of treatments for metastatic castration-resistant prostate cancer: Outcomes of a Belgian and Dutch multidisciplinary consensus meeting

By: C. Artigas MD, PhD, A.M. Bergman MD, PhD, M. Gizzi MD, I.J. de Jong MD, PhD, D.E. Oprea-Lager MD, PhD, W.J.G. Oyen MD, PhD, M. Strijbos MD, PhD

SUMMARY

The life expectancy and quality of life of patients with metastatic castration-resistant prostate cancer (mCRPC) continue to improve with the registration of new therapies. However, for individual patients, the appropriateness and optimal sequence of taxanes, radium-223, androgen receptor pathway inhibitors and lutetium-177-prostate-specific membrane antigen (PSMA) remains to be determined. To assess the current positioning of radium-223 and lutetium-177-PSMA as treatments for mCRPC, a consensus meeting with a multidisciplinary panel of experts from the Netherlands and Belgium was held. This article summarises the panel’s guidance on preferred sequences and the discussions of that meeting.

(BELG J MED ONCOL 2024;18(7):258–267)

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